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Did you mean ywhae and neoplasms (159 results)?
[miR-16-5p regulates apoptosis and migration of drug-resistant breast cancer cells by targeting YWHAQ].
Zhu H, Mao H, Tao S, Wang W, Chen C, Yang Q. Zhu H, et al. Nan Fang Yi Ke Da Xue Xue Bao. 2022 Oct 20;42(10):1476-1485. doi: 10.12122/j.issn.1673-4254.2022.10.06. Nan Fang Yi Ke Da Xue Xue Bao. 2022. PMID: 36329581 Free PMC article. Chinese.
The cells were transfected with a miR-16-5p mimics, a miR-16-5p inhibitor, a specific siRNA targeting YWHAQ (si-YWHAQ), or both the miR-16-5p mimics and si-YWHAQ, and the changes in cellular expressions of YWHAQ, Bcl-2 and Bax were detected using Weste …
The cells were transfected with a miR-16-5p mimics, a miR-16-5p inhibitor, a specific siRNA targeting YWHAQ (si-YWHAQ), or bot …
Cautions should be taken when using cell models for gastric cancer research.
Cai S, Yao D, Zhang Y, Li Z, Li X, Li L. Cai S, et al. Gene. 2022 Jan 5;806:145922. doi: 10.1016/j.gene.2021.145922. Epub 2021 Aug 26. Gene. 2022. PMID: 34454032
Substantial differences were also found between DEGs of cancer tissues (TGCA)/ healthy tissues (GTEx) pair and cell lines (CCLE)/ healthy tissues (GTEx) pair, which confirmed the significant differences between primary cancer and cancer cell lines. Moreover, elevated expression o …
Substantial differences were also found between DEGs of cancer tissues (TGCA)/ healthy tissues (GTEx) pair and cell lines (CCLE)/ healthy ti …
Identification of Proteomic Biomarkers in Proliferative Verrucous Leukoplakia through Liquid Chromatography With Tandem Mass Spectrometry.
Arroyo E, Pérez Sayáns M, Bravo SB, de Oliveira Barbeiro C, Paravani Palaçon M, Chamorro Petronacci CM, García Vence M, Chantada Vázquez MDP, Blanco Carrión A, Suárez Peñaranda JM, García García A, Gándara Vila P, Días Almeida J, Veríssimo da Costa GC, Sousa Nogueira FC, Medeiros Evaristo JA, de Abreu Pereira D, Rintala M, Salo T, Rautava J, Padín Iruegas E, Oliveira Alves MG, Morandin Ferrisse T, Albergoni da Silveira H, Esquiche León J, Vilela Silva E, Flores IL, Bufalino A. Arroyo E, et al. Lab Invest. 2023 Oct;103(10):100222. doi: 10.1016/j.labinv.2023.100222. Epub 2023 Jul 26. Lab Invest. 2023. PMID: 37507024
In addition, liquid chromatography with tandem mass spectrometry analyses showed that calreticulin (CALR), receptor of activated protein C kinase 1 (RACK1), and 14-3-3 Tau-protein (YWHAQ) were highly expressed in PVL samples. Immunohistochemistry validation confirmed incre …
In addition, liquid chromatography with tandem mass spectrometry analyses showed that calreticulin (CALR), receptor of activated protein C k …
Regulatory factor X5 promotes hepatocellular carcinoma progression by transactivating tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta and suppressing apoptosis.
Chen DB, Zhao YJ, Wang XY, Liao WJ, Chen P, Deng KJ, Cong X, Fei R, Wu X, Shao QX, Wei L, Xie XW, Chen HS. Chen DB, et al. Chin Med J (Engl). 2019 Jul 5;132(13):1572-1581. doi: 10.1097/CM9.0000000000000296. Chin Med J (Engl). 2019. PMID: 31188160 Free PMC article.
In addition, overexpression of YWHAQ in primary tumor was linked to poor prognosis of patients with HCC. These results demonstrated that YWHAQ was a downstream effector of RFX5 in HCC. Notably, RFX5-YWHAQ pathway could protect cells from apoptosis by suppress …
In addition, overexpression of YWHAQ in primary tumor was linked to poor prognosis of patients with HCC. These results demonstrated t …
RNA Sequencing Reveals Novel Oncogenic Fusions and Depicts Detailed Fusion Transcripts of FN1-FGFR1 in Phosphaturic Mesenchymal Tumors.
Liu X, Yin X, Li D, Li K, Zhang H, Lu J, Zhou L, Gao J, Wang J, Wu H, Liang Z. Liu X, et al. Mod Pathol. 2023 Oct;36(10):100266. doi: 10.1016/j.modpat.2023.100266. Epub 2023 Jun 28. Mod Pathol. 2023. PMID: 37391169
Phosphaturic mesenchymal tumors (PMTs) are rare neoplasms of soft tissue or bone. Although previous studies revealed that approximately 50% of PMTs harbor FN1::FGFR1 fusions, the molecular mechanisms in the remaining cases are largely unknown. ...Other novel fusions identi …
Phosphaturic mesenchymal tumors (PMTs) are rare neoplasms of soft tissue or bone. Although previous studies revealed that approximate …
Significance of TERT Genetic Alterations and Telomere Length in Hepatocellular Carcinoma.
Jang JW, Kim JS, Kim HS, Tak KY, Lee SK, Nam HC, Sung PS, Kim CM, Park JY, Bae SH, Choi JY, Yoon SK. Jang JW, et al. Cancers (Basel). 2021 Apr 30;13(9):2160. doi: 10.3390/cancers13092160. Cancers (Basel). 2021. PMID: 33946181 Free PMC article.
The PPI analysis identified eight key TERT-interacting genes, namely CCT5, TUBA1B, mTOR, RPS6KB1, AKT1, WHAZ, YWHAQ, and TERT. Among these, TERT was the most strongly differentially expressed gene. ...
The PPI analysis identified eight key TERT-interacting genes, namely CCT5, TUBA1B, mTOR, RPS6KB1, AKT1, WHAZ, YWHAQ, and TERT. Among …
Peripheral blood transcriptome identifies high-risk benign and malignant breast lesions.
Hou H, Lyu Y, Jiang J, Wang M, Zhang R, Liew CC, Wang B, Cheng C. Hou H, et al. PLoS One. 2020 Jun 4;15(6):e0233713. doi: 10.1371/journal.pone.0233713. eCollection 2020. PLoS One. 2020. PMID: 32497068 Free PMC article.
Biomarker biological processes and functions were analyzed for clues to the pathogenesis of breast lesions. RESULTS: Ten gene biomarkers were identified (YWHAQ, BCLAF1, WSB1, PBX2, DDIT4, LUC7L3, FKBP1A, APP, HERC2P2, FAM126B). ...
Biomarker biological processes and functions were analyzed for clues to the pathogenesis of breast lesions. RESULTS: Ten gene biomarkers wer …
Novel biomarkers for prostate cancer including noncoding transcripts.
Romanuik TL, Ueda T, Le N, Haile S, Yong TM, Thomson T, Vessella RL, Sadar MD. Romanuik TL, et al. Am J Pathol. 2009 Dec;175(6):2264-76. doi: 10.2353/ajpath.2009.080868. Epub 2009 Nov 5. Am J Pathol. 2009. PMID: 19893039 Free PMC article.
Levels of 27 transcripts were investigated as potential novel markers for prostate cancer, including genes encoding plasma membrane proteins (ADAM2, ELOVL5, MARCKSL1, RAMP1, TMEM30A, and TMEM66); secreted proteins (SPON2, TMEM30A, TMEM66, and truncated TMEFF2 (called POP4)); intr …
Levels of 27 transcripts were investigated as potential novel markers for prostate cancer, including genes encoding plasma membrane proteins …
Comprehensive analysis of genome-wide DNA methylation across human polycystic ovary syndrome ovary granulosa cell.
Xu J, Bao X, Peng Z, Wang L, Du L, Niu W, Sun Y. Xu J, et al. Oncotarget. 2016 May 10;7(19):27899-909. doi: 10.18632/oncotarget.8544. Oncotarget. 2016. PMID: 27056885 Free PMC article.
The different methylation genes were enriched in development protein, transcription factor activity, alternative splicing, sequence-specific DNA binding and embryonic morphogenesis. YWHAQ, NCF2, DHRS9 and SCNA were up-regulation in PCOS-obesity patients with no significanc …
The different methylation genes were enriched in development protein, transcription factor activity, alternative splicing, sequence-specific …
Impact of aromatase inhibitor treatment on global gene expression and its association with antiproliferative response in ER+ breast cancer in postmenopausal patients.
Gao Q, López-Knowles E, Cheang MCU, Morden J, Ribas R, Sidhu K, Evans D, Martins V, Dodson A, Skene A, Holcombe C, Mallon E, Evans A, Bliss JM, Robertson J, Smith I, Martin LA, Dowsett M; POETIC Trial Management Group and Trialists. Gao Q, et al. Breast Cancer Res. 2019 Dec 31;22(1):2. doi: 10.1186/s13058-019-1223-z. Breast Cancer Res. 2019. PMID: 31892336 Free PMC article. Clinical Trial.

In HER2- tumours, baseline expression of 48 genes associated with poor antiproliferative response (p < 0.005) including PERP and YWHAQ, the two most significant, and the transcription co-regulators (SAP130, HDAC4, and NCOA7) which were among the top 16 most significant.

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In HER2- tumours, baseline expression of 48 genes associated with poor antiproliferative response (p < 0.005) including PERP and YWHAQ

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14 results